Hep B-Ware™

Learn how the hepatitis B virus replicates in the liver cell.

Hep B-Ware™ is part of a series of mobile educational games developed by the Institute for Molecular Medicine and Infectious Disease at Drexel University College of Medicine. Together, Hep B-Ware™, Malaria Invasion™, CD4 Hunter™, and CRISPR Cutout™ introduce players to the world of infectious disease.

Visit our website: https://drexel.edu/medicine/immid-digitalgames/

Follow us on Twitter: @Drexel_IMMID, #IMMID, #HepBWare

Game Features:

Hep B-Ware is a 7-level game in which players take the role of the hepatitis B virus (HBV) navigating the bloodstream in search of a liver cell to infect. At the end of each level, players can check their knowledge by answering a pop-quiz. Players may tap the highlighted scientific terms to learn more.

By intersecting real science, with attractive visuals and animations, and simple gameplay, each game level teaches players about essential aspects of the complex mechanism by which HBV infects liver cells.

The player will be able to identify and discuss key elements of HBV infection throughout the viral life cycle including binding, attachment and entry; uncoating and nuclear entry; transcription and translation; glycosylation of surface proteins; capsid assembly; and HBV egress.

Credits:

Producer: Brian Wigdahl Ph.D.

Project Directors: Sandra Urdaneta-Hartmann, MD, Ph.D., MBA, Mary Ann Comunale Ed.D., M.S.

Creative Director: Mary Ann Comunale Ed.D.

Game Design: Mary Ann Comunale Ed.D., Christopher Dobbins

Artwork: Daniel Dobbins

Science Content and Script Writing: Mary Ann Comunale, Ed.D., Elise Mosser, Ph.D.

Funding: Drexel University College of Medicine, Department of Microbiology and Immunology, and Institute of Molecular Medicine and Infectious Disease